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Zhenyu Ju Selected Research

Leukemia

1/2023The E3 ligase TRIM31 regulates hematopoietic stem cell homeostasis and MLL-AF9 leukemia.
11/2019SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints.
4/2016Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.
1/2013Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment.
7/2011Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.

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Zhenyu Ju Research Topics

Disease

9Neoplasms (Cancer)
03/2024 - 02/2012
5Leukemia
01/2023 - 07/2011
5Inflammation (Inflammations)
01/2021 - 12/2015
5Premature Aging
01/2019 - 01/2014
4Fibrosis (Cirrhosis)
01/2024 - 08/2008
4Wounds and Injuries (Trauma)
12/2023 - 01/2021
3Obesity
05/2024 - 12/2021
3Non-alcoholic Fatty Liver Disease
05/2024 - 01/2020
3Neoplasm Metastasis (Metastasis)
09/2023 - 06/2019
3Carcinogenesis
01/2022 - 06/2006
3Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 06/2019
3Muscle Cramp (Cramp)
08/2010 - 08/2008
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2024 - 04/2016
2Hematologic Neoplasms (Hematological Malignancy)
02/2024 - 02/2012
2Pathologic Processes
02/2024 - 01/2020
2Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 01/2022
2Hypertension (High Blood Pressure)
01/2023 - 10/2003
2Liver Neoplasms (Liver Cancer)
01/2022 - 06/2019
2Eosinophilia
01/2021 - 03/2018
2Atrophy
01/2019 - 12/2012
2Aplastic Anemia (Anemia, Hypoplastic)
01/2018 - 07/2011
2Genomic Instability
01/2014 - 01/2014
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
07/2011 - 08/2008
2Essential Hypertension
11/2003 - 10/2003
1Peripheral Nervous System Diseases (PNS Diseases)
03/2024
1Myocardial Infarction
01/2024
1Hypoxia (Hypoxemia)
01/2024
1Fatigue
01/2024
1Ischemia
12/2023
1Triple Negative Breast Neoplasms
09/2023
1Bites and Stings (Sting)
09/2023
1Breast Neoplasms (Breast Cancer)
09/2023
1Thrombosis (Thrombus)
07/2023
1Essential Thrombocythemia
07/2023
1Hyperlipidemias (Hyperlipidemia)
01/2023
1Hyperuricemia
01/2023
1Metabolic Diseases (Metabolic Disease)
01/2023
1Mitochondrial Diseases (Mitochondrial Disease)
12/2021
1Neuroblastoma
01/2021
1Neurologic Manifestations (Neurological Manifestations)
01/2021
1Asthma (Bronchial Asthma)
01/2021

Drug/Important Bio-Agent (IBA)

12Telomerase (Telomerase Reverse Transcriptase)IBA
01/2022 - 06/2006
8Proteins (Proteins, Gene)FDA Link
01/2024 - 03/2005
6telomerase RNA (bTR)IBA
01/2022 - 05/2011
3NAD (NADH)IBA
01/2023 - 01/2020
3Biomarkers (Surrogate Marker)IBA
01/2020 - 08/2008
3ChitinasesIBA
06/2019 - 08/2008
3StathminIBA
10/2011 - 08/2008
2AcidsIBA
01/2021 - 12/2012
2LipidsIBA
01/2021 - 01/2020
2LigandsIBA
01/2021 - 04/2020
2CytokinesIBA
01/2021 - 04/2020
2CathelicidinsIBA
03/2020 - 01/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 11/2018
2Neutralizing AntibodiesIBA
01/2020 - 03/2018
2Hexosaminidases (Hexosaminidase)IBA
10/2011 - 08/2010
2Peptide Elongation Factor 1 (EF-1)IBA
08/2010 - 08/2008
1Dietary Fats (Dietary Fat)IBA
05/2024
1UbiquitinIBA
03/2024
1Paclitaxel (Taxol)FDA LinkGeneric
03/2024
1IronIBA
02/2024
1Ferritins (Ferritin)IBA
02/2024
1Lactic Acid (Lactate)FDA LinkGeneric
02/2024
1PTEN-induced putative kinaseIBA
01/2024
1Hemoglobins (Hemoglobin)IBA
01/2024
1radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA
01/2024
1Silybin (Lagosa)IBA
12/2023
1Phospholipid Hydroperoxide Glutathione PeroxidaseIBA
12/2023
1SilymarinIBA
12/2023
1manganese carbonateIBA
09/2023
1InterferonsIBA
09/2023
1CarbonatesIBA
09/2023
1Immune Checkpoint InhibitorsIBA
09/2023
1ManganeseIBA
09/2023
1TelluriumIBA
09/2023
1CalreticulinIBA
07/2023
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2023
1Fatty Acids (Saturated Fatty Acids)IBA
01/2022
1Triglycerides (Triacylglycerol)IBA
01/2022
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
01/2022
1Immunologic Factors (Immunomodulators)IBA
12/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021
1Interleukin-27 (Interleukin 27)IBA
12/2021
1ChemokinesIBA
01/2021
1OvalbuminIBA
01/2021
1CC ChemokinesIBA
01/2021
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2021
1Circular RNAIBA
01/2021
1BX 471IBA
01/2021
1SincalideFDA Link
01/2021
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2021
1Fluorouracil (Carac)FDA LinkGeneric
04/2020
1CXC ChemokinesIBA
04/2020

Therapy/Procedure

3Drug Therapy (Chemotherapy)
03/2024 - 11/2019
3Therapeutics
09/2023 - 01/2019
1Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2024
1Radiotherapy
09/2023
1Radioimmunotherapy
09/2023
1Bariatric Surgery
12/2021
1Immunotherapy
12/2021